Effect of extracts of astralus on learning,memory and immune function in mice
- VernacularTitle:黄芪提取物对小鼠学习记忆及免疫功能的影响
- Author:
Yan ZHANG
;
Liang MING
;
Wei-Ping LI
;
Jing-Pei LI
;
Min-Zhu CHEN
;
- Publication Type:Journal Article
- Keywords:
extracts of astralus;
cytoxan;
memory;
immune function
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim The effect of extracts of astralus(EA) on learning, memory and immune function of CTX treated mice was observed.Methods The step-down test was adopted to investigate learning and memory in mice; the method of enveloping CRBC was adopted to explore the function of macrophage in abdominal cavity; 3H-TdR marking method was used to observe the prolifernation of T lymphocytes and the method of ELISA was applied to measure the concentration of IFN-? in blood. Results EA (25 mg?kg-1, 50 mg?kg-1,ig, 21 d ) could boost learning and memory , enhance the phagocytic activity of monocytes and the proliferation of T lymphocytes of CTX treated mice, and increase the concentration of IFN-? in blood of CTX treated mice. Conclusion EA not only promote learning and memory, but regulate immune function.
