Effects of dialyzed membrane on TGF-?1 and MCP-1 plasma levels in hemodialysis patients
- VernacularTitle:透析膜对血液透析患者外周血转化生长因子?1及单核细胞趋化蛋白-1水平的影响
- Author:
Yong GU
;
Yonggui WU
;
Jianghua ZHOU
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Dialyzed membrane;
Transforming growth factor;
Monocyte chemoattractant protein
- From:
Chinese Journal of Nephrology
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate effects of different dialyzed membrane on transforming growth factor(TGF-?1 ) and monocyte chemoattractant protein(MCP-1 ) plasma levels in maintenance hemodialysis (MHD) patients. Methods The plasma concentrations of TGF-?1 and MCP-1 were measured by ELISA assay in well-matched uremic patients undergoing maintenance hemodialysis with either cuprophane (CU, n = 27 ) or polysulfone (PSU, n = 25 ). Results Compared with controls (50. 2 ? 5. 7 ng/ml), the patients on CU(82. 9 ? 9. 8 ng/ml) and PSU (65. 5 ? 6. 5 ng/ml)membranes dialysis had significantly higher mean TGF-?1 concentration (P
