Effect of alumina, magnesia, and simethicone tablet ongastric acid and pepsin activity in rats
- VernacularTitle:铝镁硅油片对大鼠胃酸和胃蛋白酶活性的影响
- Author:
Xing_Tian LI
;
Li_Jian GENG
;
Shu_Ming DING
;
- Publication Type:Journal Article
- Keywords:
alumina magnesia simethicone;
gastric acid secretion;
pepsin activity
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To study the effects of alumina, magnesia,and simethicone tabet on the secretion of gastric acid and pepsin activity in rats. Methods The pharmacodynamic indices were measured by the secretion of gastric acid and pepsin activity. Results and Conclusion Compared with the control group,alumina, magnesia, and simethicone inhibited gastric acid and increased pH of gastric juice.A significant decrease occurred in pepsin activity after a doses of 180 mg?kg-1 and 600 mg?kg-1 (P
