Immunopharmacological actions of capsule bushenyanshou in mice
- VernacularTitle:补肾延寿胶囊的免疫药理作用
- Author:
Hui WANG
;
Jin-He CHEN
;
Rui KONG
;
Qi-Xiong LI
;
Rui KONG
;
- Publication Type:Journal Article
- Keywords:
capsule bushenyanshou;
lympbocyte transformation;
charcoal particles clear-ance;
serum hemolysin;
hydrocortisone treatment;
hypersensitivity
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim The effect of capsule bushenyanshou (BSYS), a compound of traditional Chinesemedicine, on the immunopharmacological activities of mice was investigated. MethodsThe indexes of immunopharmacological activity, such as the clearance rate of charcoalparticles, the lymphocyte transformation and the content of serum hemolysin, were mea-sured. Results Capsule BSYS (400, 800 mg?kg-1, qd ? 12) markedly increased theclearance rate of iv charcoal particles and 1he lymphocyte transformation stimulated invivo by PHA in mice. In hydrocortisone -treated mice(15 mg? kg-1, sc, qd ? 5), capsuleBSYS significantly enhanced the content of serum hemolysin and the weights of spleenand thymus. The results also demonstrated capsule BSYS performed a sighted inhibition ofthe delayed type hypersensitivity in mice. Conclusion Capsule BSYS has the capacity ofimmunological intensification and regulation.
