Clinical use of mycophenolate mofetil in renal taransplation
- VernacularTitle:霉酚酸酯在肾移植术后的临床应用
- Author:
Ya-Lin DONG
;
Mao-Yi WANG
;
Meng HUANG
;
Pu-Xun TIAN
;
Sheng-Qiang PANG
;
- Publication Type:Journal Article
- Keywords:
mycophenolate mofetil;
cyclosporine A:renal transplants;
clinic
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim To monitor the whole blood trough concentration of cyclosporine A (CsA) in renaltransplant recipients reciving triple therapy with mycophenolate mofetil, cyclosporine andprednisone and to establish an optimal therapeutic window of CsA. Methods Sampleswere measured by specific fluorescence polarization immunoassay. According to the timeafter operation and different therapy plan, the whole blood trough concentration of CsA ineach group was compared with that in control group.Results The optimal therapeuticwindow of CsA with MMF plan was 150~300 ?g? L-1 (less than one month after op-eration), 120~260?g?L-1 (1~
