Clinical efficacy of anti-hyperetnsive drug Iosartan in hypretensive patients with left ventricular hypertrophy
- VernacularTitle:氯沙坦治疗高血压病左室肥厚的临床疗效
- Author:
Zhi-An JIANG
;
Xiao-Guang ZHANG
;
Wen-Liang XIAO
;
Wei-Jiang ZHAO
;
- Publication Type:Journal Article
- Keywords:
hypertension;
left ventricular hypertrophy/drug therapy;
losartan/therapyuse;
ambulatory blood pressure monitoring;
color doppler echocardiography/methods
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Aim The study is to observe the clinical efficacy of losartan in hypertentive patientswith left ventricular hypertrophy. Methods 21 case were given losartan for 20 wk and 24h ambulatory blood pressure monitoring and color doppler echocardiography were per-formed in the patients before and after treatment.Results The 24 h SBP, 24 h DBP,dDBP, nSBP were from (151 ? 15) 、(93 ?9)、(155 ? 15)、(96 ? 10)、(146 ? 16)、(88 ? 11)mmHg before treatment to (132 ? 11)、(82 ? 8)、(137 ? 12)、(88 ? 9)、(120 ? 9)、(120 ? 15)、(74 ? 9) mmHg after treatment respectively and the IVST, PWT and LVMI were from(14.2 ? 1 .5) mm、(13. 9 ? 1. 45) mm、(152. 1 ? 24. 2) g? m2-1 BSA before treatment to(12. 1 ? 1. 31) mm、 (12. 2 ? 1. 41) mm、(130. 6 ? 23. 1) g? m2-1 BSA after treatment re-spectively. All the parameters after treatment in the patients were significantly decreased ascompared with those before treatment (P
