A STUDY ON EVALUATION OF EFFICACY OF CHEMOTHERAPY FOR SCHISTOSOMIASIS WITH FRACTION ANTIGEN OF SOLUBLE EGG ANTIGEN OF SCHISTOSOMA JAPONICUM
- VernacularTitle:日本血吸虫虫卵组分抗原疗效考核价值的研究
- Author:
Yinchang ZHU
;
Wanquan HUA
;
Yunjuan LIU
;
Wei HE
;
Yongliang XU
;
- Publication Type:Journal Article
- Keywords:
fraction antigen of SEA,schistosomiasis ,evaluation of chemotherapy efficacy
- From:
Chinese Journal of Schistosomiasis Control
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
This study reported the primary application of FA-ELISA from 107-121kDa fration antibody of Schistosoma Japonicum for detection of the short-term antibody in patients with schistosomiasis. The result showed that this method provided high sensitivity (with positive rate of 93. 33% with 30 cases of schistosomiasis) and good specificity (no false postive in 60 health objects). When one group of schistosome patients were examined with FA -ELISA and with the routine SEA-ELISA before chemotherapy and at 8 months,1 year and 1. 5 year after treatment,it showed good property for evaluation of chemotherapy efficacy with FA -ELISA,which was much better than the routine method.