ANALYSIS ON EIGHT ANTIGEN PREPARATIONS OF SCHISTOSOMA JAPONICUM AND THEIR REACTIVITY WITH SERA FROM PATIENTS OF DIFFERENT STAGES
- VernacularTitle:8种日本血吸虫抗原的分析及其与不同病期血吸虫病人血清的反应性研究
- Author:
Zouhua MAO
;
Yunhe LI
;
- Publication Type:Journal Article
- From:
Chinese Journal of Schistosomiasis Control
1989;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Eight antigen preparations of schistosama japonicum. i. e. freezethawed antigens (FFT, F-MFT), saline-extract antigens (FE. F-ME, ME) SEA and AWA, were separated by SDS-PAGE. The results showed different fractional proteins among the eight antigens. These above mentioned antigens were used to detect sera from patients of different stages of schis-tosomiasis by means of ELIB. It demonstrated that the defined .fractional proteins below 60KD could be recognized by sera from acute schistosomiasis, the defined fractional proteins over 60KD recognized preferentially by sera from advanced schistosomiasis, while the fractional proteins of 87KD, 70KD, 60KD, 31KD and 18KD of S. japanicum antigens could be recognized by almost all sera from patients of different stages.
