EFFECT OF LEVO-PRAZIQUANTEL ON MIRACIDIA AND CERCARIA OF SCHISTOSOMA JAPONICUM
- VernacularTitle:左旋吡喹酮对日本血吸虫毛蚴和尾蚴作用的观察
- Author:
Bijia DENG
;
Weineng LIAN
;
Caizhong WANG
;
- Publication Type:Journal Article
- From:
Chinese Journal of Schistosomiasis Control
1989;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The antischistosomal effects of Levo-praziquantel (L-PZQ) compared with racemic prazi-quantel (dL-PZQ) in vitro on miracidium and cercaria of Schistosoma japonicum were reported in this paper. The results indicated that the schistosomicidal effect on the two larval stages of the parasite induced by L-PZQ (0. 2 ?g/ml) and double amount of dL-PZQ (0. 4?g/ml) had no significant difference. Miracidial stage was more sensitive to the drugs than the cer-carial stage. The schistosomicidal mechanism caused by L-PZQ was discussed briefly.
