Prevention of Sciatic Denervation Disuse Osteoporosis in Rat Tibia with Capacitively Coupled Electrical Stimulation
- VernacularTitle:耦合电容电场预防鼠废用性骨质疏松症的实验研究
- Author:
Ming LI
;
Zhishan LIU
;
Jianzhang GAO
;
Ming YIN
;
Zhifong ZHANG
;
Zhongming CHEN
;
- Publication Type:Journal Article
- Keywords:
electrical field;
osteoporosis;
rats
- From:
Academic Journal of Second Military Medical University
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Sciatic neurectomy was performed on the right limb in 30 rats divided into three groups. On the first postoperative days, stainless steel capacitor plates were applied parallel to each other over the midtibial region of the right, neurectomized limb m each animal in the latter two groups, which were stimulated continuously with a 60kHz sinawave signal delivering 5-10V from peak to peak. The first group was served as controls and received no electrical stimulation. At the completion of 12d of electrical stimulation, all rats were sacrificed. A statistically significant enhancement of wet weight, dry weight, ashed weight, ultimate strength and bone density occurred in the stimulated, denervated tibiae of the experimental animals compared with the nonstimulated, denervated tibiae of the control animals. The results show that a sciatic neurectomized osteoporosis was prevented in the tibiae by a capacitively coupled electrical field.
