AGE-RELATED CHANGES OF SERUM LIPID PEROXIDE, ANTIOXIDASE, COPPER, ZINC AND SELENIUM
- VernacularTitle:人体血清过氧化脂质、抗氧化酶、铜、锌及硒与增龄的关系
- Author:
Wenmin ZHANG
;
Yuping YUE
;
Manling HU
;
Yuliang ZHOU
;
Guangyu ZHOU
;
Tingyin LI
;
- Publication Type:Journal Article
- Keywords:
aging LPO SOD GSH-Px Cu Zn Se
- From:
Acta Nutrimenta Sinica
1956;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The age-related changes of serum lipid peroxide (LPO), RBC supero-xide dismutase activity (SOD) and glutathione peroxidase activity (GSH-Px), Cu, Zn and Se of blood were observed in 217 normal male persons aged 6~82. It was found that LPO increased significantly with age and SOD, GSH-Px decreased significantly in the elderly (60-70yrs). Blood Zn, Cu and Zn/Cu were highest in the childhood and lowest in the elderly. No significant change of Se with age was observed.The stepwise regression analysis showed that the factors influencing aging mainly were LPO and GSH-Px. It seems that LPO can be used as an indicator of aging.LPO was positively but GSH-Px, SOD, Zn and Cu negatively correlated with aging.
