MECHANISM OF KILLING SCHISTOSOMA JAPONICUM (CHINESE STRAIN)SCHISTOSOMULA IN VITRO. ANTIBODY-DEPENDENT MURINE NEUTROPHIL-MEDIATED CYTOTOXICITY AGAINST SCHISTOSOMULA.
- VernacularTitle:日本血吸虫(中国大陆株)童虫杀伤机理的体外研究-抗体依赖的小鼠中性粒细胞介导的细胞毒作用
- Author:
Yinlong CAI
;
Guanling WU
;
Weixian ZHAO
;
- Publication Type:Journal Article
- From:
Chinese Journal of Schistosomiasis Control
1989;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
In this study, antibody-dependent murine neutrophil-mediated cytotoxicity (ADCC)against schistosomula of Schistosoma japonicum (Chinese strain) were demonstrated in vitro by use of immune effector mechanism analysis system. The results showed that neutrophils from the normal mice could mediate the antibody-dependent ADCC reaction against the schistosomula of Schistosoma japonicum, This ADCC reaction was not dependent on the complements, the complements could not enhance the ADCC reaction mediated by the neutrophils.