A COMPARATION OF ANTIMALARIAL EFFECT OF TWENTY FOUR CHEMICAL COMPOUNDS IN FOUR DAY SUPPRESIVE TEST IN MICE AND IN CULTURE
- VernacularTitle:若干药物对体外培养恶性疟原虫及鼠体内约氏疟原虫抑制作用的比较
- Author:
Mingxian ZHOU
;
Xingqing PAN
;
- Publication Type:Journal Article
- Keywords:
P. yoelii;
P. falciparum;
Antimalarial effect
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The antimalarial effects of 24 chemical compounds on Plasmodium yoelii in mice and on Plasmodium falciparum in culture were observed . The results from both tests for most compounds are parallel or comparable, except few compounds such as Hydroxyurea and Lincomycin.What suitable methods may be used for preliminary screening of antimalarials are discussed.
