EXPERIMENTAL STUDIES ON THE EFFECTS OF TSCP, TSCC ON BLOOD PLATELET FUNCTION AND THEIR MECHANISM
- VernacularTitle:荫风轮、风轮菜总皂甙对血小板功能影响及机理的研究
- Author:
Qingyun LIU
;
Daiyin PENG
;
Min LU
;
Min DAI
;
- Publication Type:Journal Article
- Keywords:
Total saponins of Clinopodium Polycephalum and clinopodium Chinese;
Platelet aggregation and adhesion;
cAMP;
TXB_2
- From:
Chinese Pharmacological Bulletin
1987;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of TSCP and TSCC on aggregation and adhesion of blood platelets were measured by turbidimetric method and salzman method respectively. TSCP and TSCC strongly increase mouse and rat platelet aggregation and platelet adhesion. These effects are important for blood coagulation. cAMP and TXB2 levels in plasma and platelet were determind by RIA TSCP significantly increased the TXB2 level in plasma and platelet. This effect may be the main mechanism of increasing platelet aggregation by TSCP.
