THE PERMEABILITY OF BLOOD-BRAIN BARRIER AND PLACENTA TO SELENIUM IN RAT
- VernacularTitle:口服补充无机硒通过血脑屏障和胎盘屏障的实验研究
- Author:
Zonghao ZHANG
;
Qihua ZUO
;
Ruiquan TIAN
;
Gang YUAN
;
- Publication Type:Journal Article
- Keywords:
selenium blood-brain barrier placenta
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
15 rat dams were divided into 2 groups: selenium treated group drank water containing 2 ppm selenium during pregnancy and breast-feeding period, control group drank tap water. The concentration of selenium in brain tissue for dams were 0.73 ?0.11 (Se-treated) and 0.54 ?0.09 ug/g wet tissue (control), for neonates 0.32?0.02 (Se-treated) and 0.25 ? 0.03 (control), and for 20 days old pups 0.53?0.04 (Se-treated) and 0.44?0.06 (control). The results showed that the selenium administered orally could be transfered through placenta or blood-brain barrier of fetus, young pup and adult rat.
