Research Advance in Relationship between Environmental Estrogens and Disorders of Male Sex Differentiation
- VernacularTitle:环境雌激素对雄性性分化影响的研究进展
- Author:
Cong ZOU
;
Xiao-Gang LIAO
;
- Publication Type:Journal Article
- Keywords:
Environmental estrogens;
Male;
Disorders of sex differentiation;
Mechanism
- From:
Journal of Environment and Health
2007;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
The reproductive toxicity of environmental estrogens(EEs)has become an extensively studied subject in environmental science and reproductive medicine nowadays.Many epidemiology data and experimental evidences indicated that EEs may significantly cause the disorders of male sex differentiation such as microphallus,hypospadia,cryptorchidism and masculinization behavior disorder and so on.The mechanism includes estrogenic activity,anti-androgenic activity as well as other feedback regulation and signal transmission which influence hormones metabolism.
