Effect of Electromagnetic Irradiation on Activity of Protein Kinase C in Rabbit Cerebellum
- VernacularTitle:电磁辐射对家兔小脑蛋白激酶C活力的影响
- Author:
Yong LIU
;
Wei-Chu HUANG
;
Xu-Hao CHENG
;
Al ET
;
- Publication Type:Journal Article
- Keywords:
Radiation;
Cerebellum;
Protein kinase C;
Rabbit
- From:
Journal of Environment and Health
2007;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of electromagnetic irradiation on the activity of protein kinase C(PKC)in the cerebellum of rabbit.Methods Thirty rabbits were randomly divided into control and electromagnetic irradi.ation group (including 0 hour,3 hours,12 hours,24 hours and 72 hours subgroups after irradiation),rabbits in the electromagnetic irradiation group were exposed to 65 mW/cm~2 S frequency range electromagnetic irradiation for 30 minutes,the rectal temperature was taken immediately after irradiation and the specific absorption rate(SAR)values were calculated,the activity of PKC the cerebellum was determined with improved TaKai method.Results The rectal temperature of rabbits increased 2.35 ℃ after irradiation,SAR value was 4.54 kcal/kg.PKC activity decreased significantly after irradiation.Conclusion After 30 min of electromagnetic irradiation at 65 mW/cm~2,obvious heating effect will be detected in the rabbit and PKC activity in the cerebellum decreased significantly.
