Clinical significance of detecting serum CYFRA21-1,VEGF and PDGF in patients with non-small cell lung cancer
- VernacularTitle:非小细胞肺癌血清CYFRA21-1和VEGF及PDGF联合检测的意义
- Author:
Yan DU
;
Jing-Min ZHOU
;
Jian-Wen QIN
;
Shu-Ping MA
;
Dong-Sheng SHI
;
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small cell lung;
Keratin-19;
Vascular endothelial growth factor;
Platelet-derived growth factor
- From:
Cancer Research and Clinic
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnosis and TNM stage effect of serum CYFRA21-1,VEGF and PDGF in patients with non-small cell lung cancer.Methods The electrochemiluminescence immunoas- say was used to detect serum CYFRA21-1,and the sandwich enzyme-linked immunoabsorbentassay(ELISA) was used to detect serum VEGF and PDGF in patients with non-small cell lung cancer and 30 normal healthy controls.Results Compared with healthy control group,the level of serum CYFRA21-1,VEGF and PDGF in non-small cell lung cancer group were much higher(P0.05).The serum CYFRA21-1 level was positively correlated with VEGF and PDGF(P