Expression and clinical relativity of vascular endothelial growth factor in human lung cancer
- VernacularTitle:血管内皮生长因子在非小细胞肺癌中的表达及临床相关性研究
- Author:
Bo JIANG
;
Can-Zhen ZHANG
;
Jin-Qi ZHAO
;
Wei-Qi WANG
;
Cong-Guo JIN
;
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
Vascular endothelial growth factors;
Prognosis
- From:
Cancer Research and Clinic
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression difference of vascular endothelial growth factor (VEGF)between lung cancer and lung benign disease,and its relation to clinical characteristics and prognosis of non-small cell lung cancer(NSCLC),and to research the possible role of VEGF in the growth of lung can- cer.Methods The expression of VEGF and microvascular density(MVD)were detected in 60 lung cancer tissues and 30 lung benign disease tissues after operation by immunohistochemical method and put up statisti- cal analysis.Results The positive rate of VEGF expression(63%)and MVD(45.13?10.27)in lung cancer tissues were both higher than those in lung benign disease tissues(27%,33?6.49)(P
