Pioglitazone reduces expression of advanced glycation end product receptor mRNA in renal cortex of streptozotocin-induced diabetic rats
- VernacularTitle:吡格列酮减少链脲佐菌素诱导的糖尿病大鼠肾皮质糖基化终产物受体mRNA的表达
- Author:
Jian-Guo SHEN
;
Jing-Xia KONG
;
Yuan RUAN
;
Zhong-Hang TONG
;
- Publication Type:Journal Article
- Keywords:
Diabetic mellitus;
experimental;
Streptozotocin;
Pioglitazone;
Receptor;
glycosylation end products;
advanced
- From:
Chinese Journal of Endocrinology and Metabolism
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of pioglitazone on mRNA expression of advanced glycosylation end products(AGE) receptor(RAGE)was observed in renal cortex of streptozotocin-induced diabetic rats.The RAGE mRNA expression was significantly raised in diabetic control group as compared with that in the normal control group(P