Auxiliary diagnosis of aerobic forearm exercise in mitochondriai myopathy and encephalopathy
- VernacularTitle:有氧前臂运动试验在线粒体肌病及脑肌病筛选中的应用
- Author:
Jian-Hua CHEN
;
Li-Ying CUI
;
Lin CHEN
;
Yu-Pu GUO
;
Jun GAO
;
Ling QIU
;
- Publication Type:Journal Article
- Keywords:
Mitochondrial myopathies;
Mitochondrial encephalomyopathies;
Exercise test;
Blood gas analysis;
Lactate acid
- From:
Chinese Journal of Neurology
2005;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate blood gas analysis and lactic acid evaluation in aerobic forearm exercise and the significance of aerobic forearm exercise for the auxiliary diagnosis of mitochondrial myopathy and encephalopathy patients.Methods Forty-two patients with mitochondrial myopathy and encephalopathy patients, 40 healthy control, and 40 patients control were studied.They performed a protocol under aerobic exercise conditions, consisting of intermittent forearm exercise for 4 minutes at 40% of intented maximal voluntary contraction force.Blood samples were collected to monitor blood gas and plasma lactate before, during arid after exercise.Results During exercise venous PO_2(mm Hg, 1 mm Hg=0.133 kPa)decreased in mitochondrial myopathy and encephalopathy patients from 41.2?12.6 to 39.5?16.2, whereas PO_2 fell from 50.5?14.4 to 30.8?13.1 in healthy control and from 50.1?7.9 to 44.3?35.5 in patient control.Venous PO_2 decreased much more in healthy control group than the other 2 groups(F= 6.34,P
