The effects of molecules of the surface of colon carcinoma cells
- VernacularTitle:灭活肠球菌抗结肠肿瘤免疫效应
- Author:
Ming-E SUN
;
Hui-Jun XU
;
Dong ZHANG
;
- Publication Type:Journal Article
- Keywords:
Enterococcus;
Colonic neoplasms;
HT29 cells
- From:
Cancer Research and Clinic
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of the HLA-Ⅰ and co-stimulators CD_(80)and CD_(86)on HT-29 cells surface, after heat killed Bifidobacterium and HT-29 cells were mingled culturing for 12 hours. Methods The HLA-Ⅰ and co-stimulators CD_(80)and CD_(86)on HT-29 cells surface were measured by Flow Cytometer. Results Heat killed Bifidobacterium can improve the expressions of HLA-1, CD_(80)and CD_(86)on HT-29 cells significantly, the livability of colon carcinoma cell was more than 90 %. Conclusion Heat killed Bifidobacterium have potential antitumorous features.
