The clinical significance of the epithelial cellular adhesion molecule(Ep-CAM)expression in esophageal squamous cell carcinoma(SCC)
- VernacularTitle:食管癌组织上皮细胞黏附分子表达的临床意义
- Author:
Hui-Ning LIU
;
Jian-Ling SU
;
Shao-Hui ZHOU
;
Yun-Jie ZHANG
;
Xue-Min LI
;
Zeng-Lin FAN
;
Li-Jun LIU
;
Jun-Feng LIU
;
Hui-En WANG
;
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Epithelial cellular adhesion molecule;
Immunohistochem-istry
- From:
Cancer Research and Clinic
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical significance of epithelial cellular adhesion molecule (Ep-CAM)expression in esophageal squamous cell carcinoma(SCC).Methods The Ep-CAM expression was immunohistochemically investigated in 70 normal esophageal mucosas,SCCs and 72 lymph nodes.Results Ep-CAM expression was observed in 94.3% of the tumors,but no expression in the normal mucosa.The Ep- CAM expression was not significantly different between different tumor scales and tumors invading depths,its expression level was relevant with the tumors differentiation and lymph node metastases(P
