The expression and correlation of VEGF and MMP-2 in rectal carcinoma
- VernacularTitle:血管内皮生长因子、基质金属蛋白酶-2在直肠癌中的表达及其相关性
- Author:
Jian-Jun WANG
;
Zheng-De ZHU
;
Zhi-Su LIU
;
Cong-Qing JIANG
;
Qun QIAN
;
Yu-Feng YUAN
;
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
VEGF;
MMP-2;
Immunohistochemistry
- From:
Cancer Research and Clinic
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression and the relation of vascular endothelial growth factor (VEGF)and matrix metal proteinase-2(MMP-2)in rectal cancer and evaluate their roles in rectal carcinogen- esis and development.Methods The expression of VEGF and MMP-2 in 52 cases of rectal cancer was de- tected by immunohistochemical SP technique.12 cases normal rectal tissue served as the control group.Re- suits The expression of VEGF in rectal carcinoma(67.3 %)was much higher than that in control group(P
