Expression of caspase-3 survivin CyclinD1 and p27 in gastric carcinoma and their significance
- VernacularTitle:caspase-3、survivin、CyclinD1及p27在胃癌中的表达及其意义
- Author:
Zhao-Xia YAN
;
Quan-Hong WANG
;
Feng-Ling HE
;
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Apoptosis;
Immunohistochemistry
- From:
Cancer Research and Clinic
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of caspase-3,survivin,CyclinD1 and P27 in gastric carcinoma(CA2)and the relationship between the biomarkers and clinical pathological parameters. Methods Immunohistochemical Ready-to-use two-steps method was performed to research the expression of the four proteins in 72 cases of GC,and 54 cases of normal gastric mucosa.Results The expression level of caspase- 3 and p27 protein in GC was significantly lower than that in normal gastric mucosa(P
