Comparison of once daily and twice daily administration of glimepiride with same total dosage in type 2 diabetes
- VernacularTitle:2型糖尿病患者一次顿服或分两次服用2mg格列美脲的疗效比较
- Author:
Long-Yi ZENG
;
Pan-Wei MU
;
Guo-Chao ZHANG
;
Yan-Ming CHEN
;
Hai-Xia XU
;
Jing-Yi FU
;
Man-Man WANG
;
Bo-Quan JIANG
;
- Publication Type:Journal Article
- Keywords:
Glimepiride;
Diabetes mellitus;
type 2;
Blood glucose control;
Blood glucose excursion
- From:
Chinese Journal of Endocrinology and Metabolism
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
A total of 126 patients with type 2 diabetes mellitus were randomized into two groups:one received glimepiride 1 mg twice daily and the other 2 mg once daily.Fasing blood glucose(BG),BG 2 h after meals(breakfast,lunch and dinner)and HbA_(IC)were tested,△and standard deviation of the 4 point BG were calculated.It was found that two kinds of administration of glimepiride were equally effective in decreasing BG and once daily aministration could ease better the fluctuation of BG.