Reevaluation of the hypothalamic-pituitary-adrenal axis function in patients with severe sepsis or septic shock
- VernacularTitle:严重感染患者下丘脑-垂体-肾上腺轴功能的再评价
- Author:
Na CUI
;
Da-Wei LIU
;
Zheng-Pei ZENG
;
Hao WANG
;
Yun LONG
;
Hong-Zhong LIU
;
Xiao-Ting WANG
;
Xi RUI
;
- Publication Type:Journal Article
- Keywords:
Sepsis;
Shock,septic;
Hypothalamo-pituitary-adrenal axis;
ACTH-stimulating test
- From:
Chinese Journal of Endocrinology and Metabolism
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Serum cortisol and plasma ACTH were determined in 10 patients with severe sepsis and 12 with septic shock on day 1,3,5 after diagnosis were made,and the data were compared with 12 control patients. To evaluate the hypothalamic-pituitary-adrenal(HPA)axis function in patients with severe sepsis and septic shock,1?g ACTH stimulation test was applied after hormone concentrations were obtained on day 1.Compared with the control patients,ACTH level was significantly higher in patients with severe sepsis and lower in septic shock(P
