Targeted therapy of mantle cell lymphoma
- VernacularTitle:套细胞淋巴瘤的靶向治疗
- Author:
Zhao-Yan WANG
;
Er-Bing WANG
;
- Publication Type:Journal Article
- Keywords:
Lymphoma,mantle-cell;
Targeted therapy
- From:
Cancer Research and Clinic
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Mantle cell lymphoma(MCL)is one of the most frustrating diseases because it exhibits the worst features of both aggressive non-Hodgkin Lymphoma(NHL)and indolent NHL.It develops rapidly like the former,and it is incurable and lacks of better therapeutic options like the latter.Clinical researchs confirm the activity of rituximab as a single agent and combination regimens(R-Chemo)in the treatment of MCL. Bortezomab is also active in treating patients with MCL and requires further study in combination regiments. The usages of mTOR inhibitor and radioimmunotherapy represents a novel therapeutic approaches in the treatment of MCL.It is also deserved to study.
