The clinical value of England,Canada and Japanese liver transplantation criteria to predict the prognosis of the patients with chronic severe hepatitis in China
- VernacularTitle:英国、加拿大和日本肝移植标准评估我国慢性重型肝炎患者预后的价值
- Author:
Zhong-Sheng JIANG
;
Jian-Ning JIANG
;
- Publication Type:Journal Article
- Keywords:
Hepatitis,chronic;
Criterion of King's College Hospital(KCH);
Criterion of Canadian waitlisting algorithm (CanWAIT);
Criterion of Japanese liver transplantation (JLT);
Prognosis
- From:
Chinese Journal of Organ Transplantation
2005;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of King's College Hospital Criterion (KCH),Canadian Waitlisting Algorithm Criterion (CanWAIT) and Japanese Liver Transplantation Criterion (JLT) in predicting the prognosis of the patients with chronic severe hepatitis in China. Methods Fifty-five patients with chronic severe hepatitis were classified respectively by the three liver transplantation criteria.Those who were in line with the criterion were ascribed the matched criteria group (MCG),while those who were not in line with the criterion were ascribed the unmatched crite ria group (UCG).The end point of observation was the 90th day after their admission.The survival time and the mortality were compared between the MCG and UCG.The predictive ability for each cri- terion and their correlation with the clinical stages of chronic severe hepatitis were analyzed.Results Seventeen cases accorded with KCH and CanWAIT,while 38 cases did not accord with KCH and CanWAIT.The median survival time (MST) and their mortality in MCG group were 17.5 days and 100.0% respectively,while those in UCG group were 69.2 days and 34.2% respectively.Twenty- one cases accorded with JLT,while 34 cases did not accord with JLT.The MST and their mortality in MCG were 17.7 days and 95.2% respectively,while those in UCG group were 75.2 days and 29.4% repsectively.There were significant differences in MST and mortality between MCG group and UCG group with the 3 criteria (P
