The chemotherapy role of vinorelbine with relapsed breast cancer primary cells in vitro
- VernacularTitle:单药长春瑞滨对乳腺癌原代细胞杀伤效果的体外研究
- Author:
Zhi LI
;
Chun-Ping LIU
;
Peng YUAN
;
Yuan TIAN
;
Tao HUANG
;
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Vinorelbine;
Study in vitro
- From:
Cancer Research and Clinic
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To know the antitumor effect and value of vinorelbine in chemotherapy with relapsed breast cancer.Methods To receive breast cancer tissue from primary and relapsed patients by surgery,then to obtain mammary cancer cells by collagenase.The antitumor effect of 5 chemotherapy drugs with breast cancer cells was measured by culture in vitro and MTT.Results With primary cancer cells from primary breast cancer,the antitumor effect of paclitaxel and docetaxel(sensitivity is 91.04%,92.54% respec- tively) is better than adriamycin,epirubicin and gemcitabine(sensitivity is 73.13%,74.63%,71.64% re- spectively;P
