Expression of COX-2 and the relationship between COX-2 and PTEN in endometrial adenocarcinoma
- VernacularTitle:环氧化酶-2在子宫内膜样腺癌中的表达及其与PTEN的相关性
- Author:
Huan-Hua WANG
;
Yi-Lin WU
;
Zhi-Sheng ZHANG
;
Li-Ling WU
;
- Publication Type:Journal Article
- Keywords:
Endometrial neoplasms;
Epoxy compounds;
PTEN protein;
Immunohistochemistry
- From:
Cancer Research and Clinic
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression and clinical significance of COX-2 and the relation- ship between COX-2 and PTEN in endometrial adenocarcinoma(EAC).Methods The expression of COX-2, PTEN protein was detected by SP-immunohistochemical method in EAC,endometrial intraepithelial neoplasia, corresponding normal endometrium.Results The positive rates of COX-2 protein increased from normal en- dometrium(13.33%) to endometrial intraepithelial neoplasia(50.00%) and adenocarcinoma(64.58 %)(P
