Analysis on the clinical pathology of 21 cases of pulmonary sclerosing hemangioma
- VernacularTitle:肺硬化性血管瘤21例临床病理分析
- Author:
Zhan-Dong WANG
;
Jie YANG
;
Xiao-Ling WANG
;
Yue-Ping LIU
;
Yong-Jun WANG
;
Guo-Xiang WU
;
- Publication Type:Journal Article
- Keywords:
Plumonary sclerosing hemangioma;
Pathologic;
Immunohistochemistry
- From:
Cancer Research and Clinic
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and pathologic features of pulmonary sclerosing he- mangioma (PSH).Methods With clinicopathologic date of 21 cases of PSH patients obtained,all speci- mens were stained by immunohistochemical method with a panel of antibodies including CK,synaptophysin, chromogranin,actin,calretinin,F-Ⅷ,CD_(34) and vimentin.Results PSH usually affects female patients.Age ranged from 26 to 70 years old.The tumor cells showed a mixture histological pattern,with the feature of pap- illary and the proliferation of interstitutial monocyte.Immunohistochemical staining revealed that surface of the papillary cells expressed CK,monocyte expressed synaptophysin.PSH should be distinguished from bronchi- oloalveolar carcinoma,carcinoid and inflammatory pseudotumor.Conclusion PSH is a rare and potential malignant behavior tumor,and is different from benign tumor.