The study of adrenomedulin in breast cancer
- VernacularTitle:肾上腺髓质素在乳腺癌表达的研究
- Author:
Na CUI
;
Hai-Ping LI
;
Zhong-Lin FAN
;
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Adrenomedulin
- From:
Cancer Research and Clinic
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Adrenomedulin is an angiogenesis peptide that was found recently.It plays a critical role as an autocrine/paracrine tumor cell survival factor.Recently,adrenomedulin has been proved that it is overex- pressed in tumor,such as breast cancer.It may have a significant role in tumor progression and differentiation by stimulating mitogenic activities,inhibiting immune response,inhibiting apoptosis and enhancing angiogen- esis.We may realize targeted therapy tumor by intervening adrenomedulin,its receptor,and the signal con- duction pathway.
