Comparison of clinical features in type 2 diabetic patients with various lesions of diabetic nephropathy
- VernacularTitle:不同病理类型的2型糖尿病肾病患者临床特征比较
- Author:
Hong DU
;
Zheng TANG
;
Hui-Ping CHEN
;
Jian WANG
;
Zhi-Hong LIU
;
Lei-Shi LI
;
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathies;
Diffuse glomerulosclerosis;
Nodular glomerulosclerosis
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively investigate and compare the clinical features in type 2 diabetic patients with various lesions of diabetic nephropathy.Methods One hundred and fifty patients of type 2 diabetes mellitus were registered from December 1990 to April 2004,among them 73 cases of diffuse glomerulosclerosis (DIF)and 77 nodular glomerulosclerosis(NOD)were all proven by renal biopsy.Data such as the durations of diabetes mellitus and hypertension,body mass index(BMI),diabetic retinopathy,HbA_1c,plasma albumin, proteinuria,urine N-acetyl-?,-glucosaminidase,urine osmolarity,ereatinine clearance rate(Ccr)were collected and compared.Results(1)Compared with the patients with DIF,the patients with NOD had longer duration of diabetes mellitus[(122.0?8.1 vs 56.0?7.8)months,P
