Different patterns of brain activation between Alzheimer's disease with and without depression:a fMRI study during attention task
- VernacularTitle:伴有和不伴有抑郁的阿尔茨海默病患者在静音Stroop任务下脑功能激活的差异
- Author:
Hai-Tao WANG
;
Jian-Ping JIA
;
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Depression;
Attention;
Magnetic resonance imaging
- From:
Chinese Journal of Neurology
2005;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
12.Meanwhile 10 healthy elderly subjects of similar age and gender ratio were matched as controls.There was no significant difference of age,gender,education,onset duration and MMSE.Attention task was carded out with silent color-word task:all participants pressed the left or right button to select the answer of congruence or incongruence when color nouns in red,green,blue or yellow ink appearing on the left part of screen and a target color appearing on the right part of the screen by.During the tasks,reaction time,false ratio,missing ratio and fMRI image acquisition was respectively recorded,which were later analyzed on SPSS 11.0 statistical parametric mapping software 2 (SPM2) respectively.Results The reaction time in dAD,AD and control group were (2214.4?1071),(2020.6?558.3) and (840.0?254.5) ms respectively.The false ratio were 8.3%,6.9% and 0.7% respectively,and the omit ratio were 3.6%, 2.9% and 0 respectively.Either AD with or without depression was slower than the controls in reaction time (P
