Clinical application of diffusion tensor imaging in cognitive impairment of patients with acute cerebral infarction
- VernacularTitle:磁共振弥散张量成像与急性脑梗死患者认知功能的关系
- Author:
Guo-Qiang WEN
;
Xiao-Ping LIAO
;
Tao CHEN
;
Bing-Yan WANG
;
Feng OUYANG
;
Jian-Jun LI
;
Chuan-Zi LI
;
Shi-Xiong HUANG
;
Ying-Liu HUANG
;
- Publication Type:Journal Article
- Keywords:
Brain infarction;
Cognition;
Diffusion magnetic resonance imaging
- From:
Chinese Journal of Neurology
2005;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of diffusion tensor imaging(DTI)in cognitive impairment of patients with acute cerebral infarction.Methods Diffusion tensor images were obtained from 30 volunteers who underwent clinical MR imaging and were found to have no abnormalities on conventional MR images and 30 patients who were clinically diagnosed cerebral infarction and were found to have infarction lesions on conventional MR images.Color-coded FA images and three-dimensional color-coded tensor images were reconstructed.For volunteers,average apparent diffusion coefficient(ADC)and fractional anisotropy(FA)were measured in some main white matter structures of peripheral white matter, basal ganglia,and cerebral peduncle,etc.For infarction patients,ADC and FA were measured and compared between infarction lesions and corresponding contralateral normal regions.Pearson correlation analysis was used to determine correlation with cognitive impairment.Results In infarction patients group, FA and ADC of lesions unrecovered declined.Change in ADC and FA had positive correlation with cognitive impairment of patients with acute cerebral infarction.Conclusion DTI has positive correlation with cognitive impairment of patients with acute cerebral infarction.
