Clinical effect of early postoperation adjuvant intraperitoneal chemotherapy of locally advanced gastric cancer
- VernacularTitle:胃癌根治术后早期腹腔置管腔内化疗的临床意义
- Author:
Lin-Qing XI
;
Xiao-Dong ZHANG
;
Jie LI
;
Jian LI
;
Lin SHEN
;
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Antineoplastic combined chemotherapy protocols;
Peritoneal lavage
- From:
Cancer Research and Clinic
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).The most common toxicity was neutropenia and nausea.There are no serious nausea,damage of liver and kidney functions and grade 4 neutropenia in the study group.The side-ef- fects,in the study group,such as hemorrhage,infection,medicine outleakage,catheter obstruct,catheter slough,gastric-intestinal perforation,and fever did not appear.Conclusion Although this study was conduct- ed in a small number of patients and short time,compared with the control group,the study group had a ben- eficial effect in peritoneal recurrence after curative gastrectomy for advanced gastric cancer and had less side effect and good toleration.It played a role in enhancing 1-year overall survival rate.The combination of intra- venous and intraperitoneal chemotherapy after gastrectomy may have better treatment effect on gastric cancer than that of intravenous chemotherapy alone.The randomized controlled trials are required.
