The effect of blockade of rennin angiotensin system on expression of visfattn mRNA in long term high fatfed rats
- VernacularTitle:在长期高脂喂养大鼠阻断肾素血管紧张素系统对内脂素基因表达的影响
- Author:
Cui-Juan QI
;
Li YUAN
;
Xin LI
;
Guo-Ling XU
;
- Publication Type:Journal Article
- Keywords:
Insulin resistance;
Visfatin;
Renin-angiotensin system
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Visfatin was recently reported as an adipokine and was found to exert insulin-mimicking effects.The results showed that the expression of visfatin parallelled with obesity and insulin resistance in long term high fat chow-fed rats.The expression of visfatin mRNA was decreased and the insulin resistance improved after rennin-angiotensin system was blocked.Visfatin may play an important role in the pathogenesis of insulin resistance.
