The current research status of genetics of sporadic clear renal cell carcinoma
- VernacularTitle:散发性肾透明细胞癌的遗传学研究现状
- Author:
Jian-Zhong SHOU
;
Jian-Hui MA
;
- Publication Type:Journal Article
- Keywords:
Kidney neoplasms;
Adenocarcinoma,clear cell;
Genetic research
- From:
Cancer Research and Clinic
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The mechanism of the development of sporadic renal cell carcinomas is complicated,which is different from that of hereditary renal-cell carcinoma.Genetics abnormality such as loss of 3p,VHLgene mutations may help differentiate pathological subtype of renal cell carcinoma and some gene markers may be useful predictors for prognosis.The current status of genetic study in renal cell carcinomas is reviewed in this article.