Application of CK34?E12,p63 and P504S in diagnosis of prostate cancer
- VernacularTitle:CK34?E12、p63和P504S联合检测在前列腺癌诊断中的应用
- Author:
Cai-Hong WANG
;
Jin-Fen WANG
;
Zhen-Guo MI
;
Shi-Lan JIAO
;
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Immunohistochemistry;
Diagnosis;
CK34?E12;
p63;
P504S
- From:
Cancer Research and Clinic
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of CK34?E12,p63 and P504S immunostaining in diag- nosis of benign and malignant lesions of the prostate.Methods Expression of CK34?E12,p63 and P504S in 74 benign and malignant lesions of prostate,including 27 PC,6 HGPIN,10 LGPIN,3 AAH and 28 BPH were observed by immunohistochemical method.Results Expression of p63 and CK34?E12 were positive in AAH,LGPIN and BPH,all of PC were negative,the positive rate of HGPIN was 83.3%(5/6).There were sig- nificant differences in p63 and CK34?E12 expression between PC and AAH,HGPIN,LGPIN,BPH(P
