Significance of examine of??T and NKT cells in non-small-cell lung cancer
- VernacularTitle:非小细胞肺癌患者??T细胞和NKT细胞及其亚群检测的意义
- Author:
Shao-Yun ZHANG
;
Jun-Ping ZHANG
;
Su-Ying ZHANG
;
ZHAO-PEI
;
Ming-Ying SHI
;
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small-cell lung;
??T cells;
Killer cells,natural
- From:
Cancer Research and Clinic
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To open out new method,we probe into immune function of??ST and NKT cells in NSCLC.Methods The peripheral blood cells were stained with antibodies labeled with fluorescence in NSCLC,??T,NKT and their set group cells were counted with flow cytometry.Results The absolute counts of??T,CD~+_(56)??T,CD~-_(56)??T,NKT and??T~+ NKT cells in NSCLC was significantly lower than that of normal controls.The relative counts of NKT,??T~+ NKT,??T~-NKT and CD~+_56??T cells in NSCLC was not sig- nificantly lower than that of normal control.The absolute counts of??T cells in NSCLC positively correlated to the number of NKT cells,(r=0.426,P=0.009).Conclusion The absolute counts of??T,NKT and their set ground cells in NSCLC was significantly lower than that of normal controls.In NSCLC the relation of the??T and NKT had positive correlation.
