Advance on growth differentiation factor 15 and its relation with colorectal cancer
- VernacularTitle:生长分化因子15与大肠癌关系的研究进展
- Author:
Guan-Hua WANG
;
Niu-Liang CHENG
;
- Publication Type:Journal Article
- Keywords:
CRC;
Genetype
- From:
Cancer Research and Clinic
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
GDF-15,a distant member of the TGF-superfamily,is identified as an apoptotic accelerat- ing,anti-tumorigenesis and nerve2nutritional factor in varied injures and tumors and has cardioprotective ac- tivity.The characteristics and roles of GDF-15 gene/protein and antibodies are expounded besides the rela- tionship between GDF-15 serum level/genetypes and CRC.It is also discussed here that some antitumorigenic substances inducing GDF-15 in CRC tissues and CRC cells.
