Predictors of long-term remission induced by short-term intensive insulin treatment in type 2 diabetic patients
- VernacularTitle:短期胰岛素强化治疗诱导2型糖尿病患者长期缓解的预测因素
- Author:
Bo ZHANG
;
Ya-Li AN
;
Qiu-Hong GONG
;
Ying SHUAI
;
Shi BU
;
YAN-YAN
;
Jin-Ping ZHANG
;
Wen-ying YANG
;
Xue-li LIU
;
Guang-wei LI
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Intensive insulin treatment;
Long-term remission;
First-phase insulin secretion;
Tumor necrosis factor-?
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictors of long-term remission of type 2 diabetes induced by short-term intensive insulin treatment.Methods Fifty-four cases of diabetes mellitus with the duration of illness less than 5 years received an intensive insulin treatment for 2 weeks.The standard meal test and intravenous glucose tolerance test were performed at the baseline and 24 h after treatment completion respectively.Long-term remission meant that the diabetic patients should maintain the target glyeaemic control without any hypoglyeaemie agent within one year.Results The remission rate was 57.4% (31/54) overall,and even reached to 80.6% (29/36) in patients with the duration of illness less than 6 months,whereas,the remission rate was only 11.1% (2/18) in those with the duration of illness more than 12 months.In another view,the remission rate was significantly higher in the patients with fasting plasma glucose (FPG) level of less than 7 mmol/L (78.8%,26/ 33) 24 h after intensive treatment than those with FPG level of more than 7 mmol/L (23.8%,5/21,P
