Benign Pulmonary Metastasizing Leiomyomatosis: Case Report and a Review of the Literature.
10.3904/kjim.2006.21.3.173
- Author:
Young Il KWON
1
;
Tae Hyung KIM
;
Jang Won SOHN
;
Ho Joo YOON
;
Dong Ho SHIN
;
Sung Soo PARK
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. drterry@hanyang.ac.kr
- Publication Type:Case Report ; Review
- Keywords:
Benign metastasizing leiomyomatosis (BML);
Uterine leiomyoma;
C-kit (CD117)
- MeSH:
Uterine Neoplasms/*pathology/surgery;
Ovariectomy;
Middle Aged;
Lung Neoplasms/diagnosis/*secondary;
Leiomyomatosis/*pathology/surgery;
Hysterectomy;
Humans;
Female;
Disease Progression
- From:The Korean Journal of Internal Medicine
2006;21(3):173-177
- CountryRepublic of Korea
- Language:English
-
Abstract:
The authors report here on a case of a nearly asymptomatic 51-year-old Korean woman who was found to have diffuse, multiple nodules of the lungs on a routine chest radiograph. She had undergone hysterectomy 16 years previously for uterine myoma. An open lung biopsy revealed tumor that was composed of interlacing bundles of spindle cells with cigar shaped nucleus and eosinophilic myofibrils in the cytoplasm; consistent with multiple leiomyomas. The stains for SMA, desmin, MSA and Ki-67 were positive and the stain for c-kit was negative. The other stains for estrogen and progesterone receptor were positive. During the open lung biopsy procedure, all the nodules were excised. We report here on an interesting case of benign metastasizing leiomyoma (BML) in 51-year-old patient. To the best of our knowledge, this case showed the longest period of clinical progression in Korea. This is also one of a few cases in which curative excision was successfully performed.
