Relationship between adrenomedullin and diabetic tubulointerstitial injury
- VernacularTitle:肾上腺髓质素与糖尿病肾病小管间质病变的关系
- Author:
Ji-Xiang DONG
;
Jun LI
;
Ying XIE
;
Zhi-Min MA
;
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathies;
Adrenomedullin;
Tubulointerstital injury
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Forty-two patients with type 2 diabetes mellitus (DM) were refered to 3 groups:type 2 DM without diabetic nephropathy (DN),type 2 DM with DN in the initial stage and type 2 DM with DN in the clinical stage.Ten healthy subjects were served as control group.Plasma adrenomedullin (ADM),urinary?_1- microglobulin (MG) and?_2-MG were detected.The results showed that the level of plasma ADM rose gradually with the development of DN and was positively correlated with markers of tubulointerstiial injury such as urinary?_1- MG and?_2-MG (both P
