Effects of TNF-?on PPAR-?2 mRNA expression and adiponectin secretion in 3T3-L1 adipocytes
- VernacularTitle:TNF-?对3T3-L1脂肪细胞PPAR-?2 mRNA表达及脂联素分泌的影响
- Author:
Da-Tong DENG
;
You-Min WANG
;
Ling LIU
;
Guo-Ping HU
;
Ming-Gong YANG
;
Qi-Mei SHE
;
Chang-Jiang WANG
- Publication Type:Journal Article
- Keywords:
Adiponectin;
PPAR-?2;
3T3-L1 cells;
Tumor necrosis factor-?
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Undifferentiated and differentiated 3T3-L1 adipocytes were treated with 100 ng/ml tumor necrosis factor-?(TNF-?),and peroxisome proliferator-activated receptor-?2 (PPAR-?2) mRNA expression and adiponectin secretion in cultured cells were measured.The results showed that TNF-?suppressed PPAR-?2 mRNA expression and adiponeetin secretion in 3T3-L1 adipocytes (P
