Smoking inhibits expressions of insulin receptor substrate-1 mRNA and protein in rat muscle
- VernacularTitle:吸烟减少大鼠骨骼肌胰岛素受体底物1 mRNA和蛋白表达
- Author:
Ji-Wang WANG
;
Su-Hua ZHANG
;
Hao-Jie WU
;
Zhi-Hong WANG
;
Wei REN
;
- Publication Type:Journal Article
- Keywords:
Smoking;
Insulin resistance;
Insulin receptor substrate 1;
Muscle,skeletal
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Insulin receptor substance-1 (IRS-1) mRNA and protein were assayed in rat muscle of hindlamb by RT-PCR and immunohistochemistry respectively.Smoking decreased the expressions of IRS-1 mRNA and protein in rat muscle of normal chow smoking group,high fat chow smoking group and diabetic smoking group as compared with matched control groups (P
