Effects of transfection with recombinant adiponectin adeno-associated virus vectors (rAAV-Ad) on glucose production in H4IIE hepatoma cells
- VernacularTitle:小鼠脂联素重组腺相关病毒载体转染对H4IIE细胞葡萄糖生成的影响
- Author:
Miao ZHANG
;
Fang-Ping LI
;
Li-Hong CHEN
;
Jing-Yi FU
;
Zu-Zhi FU
;
Li YAN
;
Feng LI
;
Chuan YANG
;
Yan LI
- Publication Type:Journal Article
- Keywords:
Adiponectin;
Adeno-associated virus;
H4IIE cells;
Glucose production
- From:
Chinese Journal of Endocrinology and Metabolism
1985;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
H4IIE hepatoma cells transfected by recombinant adiponectin adeno-associated virus vectors were effectively mediated adiponectin gene expression and enhanced the ability of suppressing glucose production of H4IIE cells at low concentration of insulin.Improvement of the insulin sensitivity in hepatocytes may contribute to the glucose-lowering effect of adiponectin.
