Expression of P450 aromatase in endometrial carcinoma
- VernacularTitle:芳香化酶P450在子宫内膜癌中的表达及其意义
- Author:
Xue-Mei ZOU
;
Kai WU
;
Zhu-Hong XU
;
- Publication Type:Journal Article
- Keywords:
Endometrial nleoplasms;
Endometrial hyperplasia;
Immunoenzyme tezhigues;
Immunohistochemistry;
P450 aromatase
- From:
Cancer Research and Clinic
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).Immunohistochemical staining for intratumoral aromatase in endometrial cancer was positive,21(42 %)in stromal cells.The expression of P450 aromatase in stromal cells correlated positively with advanced surgical stage and histologic grade,indepedent on muscular invasion and lymph node metastasis.Conclusion Aromatase P450 play an important function in establishment and devel- opment of the endometrioid endometrial cancer.The expression of P450 aromatase in intratumoral stromal cells correlated positively with the development and prognosis of endometrioid endometrial cancer.
