Clinical significance of integrin?_5?_1,Fn and CD_(44v6) expression in ovarian epithelial neoplasms
- VernacularTitle:整合素?_5?_1、Fn及CD_(44v6)在卵巢上皮性肿瘤中的表达及其意义
- Author:
Rui-Xia CHANG
;
Jian-Ping WEI
;
Shuang-Ling JIN
;
Rui WANG
;
- Publication Type:Journal Article
- Keywords:
Ovarian epithelial neoplasms;
Integrin?_5?_1;
Fn;
CD_(44v6);
Lymphatic metastases
- From:
Cancer Research and Clinic
1997;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Through the investigating the molecular expressions of integrin?_5?_1,Fn and CD_(44v6) in ovarian epithelial neoplasms,this study is trying to explore the relationship between the lymphatic spread of the tumor with these molecules.Methods The expression of 80 cases of integrin?_5?_1,Fn and CD_(44v6) was examined through ElivisionTM immunohistochemistry method in ovarian epithelial neoplasm.The system of image analysis was used to measure the expression of various molecules quantitatively.Results Qualitative and semi-quantitative results:The expression levels of integrin?_5?_1 and Fn in the ovarian epithe- lial neoplasms had downward tendency in the order of benign,boundary and malignant neoplasms and there was a significant difference in the expression levels of integrin?_5?_1 and Fn(P
